Why Does Low Cholesterol Cause Depression?

Extremely low cholesterol has been linked to increased rates of depression and even greater rates of suicide, according to multiple studies.

Since the exact cause is unsolved, here are some possible causes.

Why Does Low Cholesterol Cause Depression?
Why Does Low Cholesterol Cause Depression?


Why Does Low Cholesterol Cause Depression?

1. Serotonin Signals Don’t Work as Well

  • The oil in your brain's cell walls is cholesterol.
  • It increases the entry and exit of serotonin, the "feel-good" hormone.
  • Serotonin's happy messages are less effective when there is insufficient cholesterol.

2. Mood Receptors Get Less Sensitive

  • To maintain the function of their serotonin "antennas," mood-regulating parts of the brain require cholesterol.
  • The brain receives fewer happy messages when cholesterol levels are low because their volume is reduced.

3. Fewer Mood-Balancing Chemicals

  • Cholesterol is used by your body to produce soothing brain chemicals.
  • You have less material to manufacture those calming remedies if your cholesterol levels are low.

4. Brain Cell Connections Weaken

  • The "wiring" between brain cells is strengthened and maintained by cholesterol.
  • These connections can become weak due to low cholesterol, which reduces brain cell communication.

What does it mean for you?

A) Cholesterol-Lowering Medicines: The majority of statin users do not experience depression. Consult your doctor if you have mood swings; sometimes, the issue is not simply your cholesterol level but also how your body processes the medication.

B) Depression Has Many Causes: Low cholesterol may be a minor factor, but other factors include stress, sleep, nutrition, heredity, and life experiences.

Speaking with your doctor is the best course of action if you are concerned about your mood or your cholesterol. They might help you in finding the ideal balance between your emotions and your head.

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